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Improving the chances of successful protein structure determination with a random forest classifier

Obtaining diffraction quality crystals remains one of the major bottlenecks in structural biology. The ability to predict the chances of crystallization from the amino-acid sequence of the protein can, at least partly, address this problem by allowing a crystallographer to select homologs that are m...

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Bibliografiske detaljer
Main Authors: Jahandideh, Samad, Jaroszewski, Lukasz, Godzik, Adam
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949519/
https://ncbi.nlm.nih.gov/pubmed/24598732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004713032070
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