Controlled release of nerve growth factor from heparin-conjugated fibrin gel within the nerve growth factor-delivering implant

OBJECTIVES: Although nerve growth factor (NGF) could promote the functional regeneration of an injured peripheral nerve, it is very difficult for NGF to sustain the therapeutic dose in the defect due to its short half-life. In this study, we loaded the NGF-bound heparin-conjugated fibrin (HCF) gel i...

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Autors principals: Lee, Jin-Yong, Kim, Soung-Min, Kim, Myung-Jin, Lee, Jong-Ho
Format: Artigo
Idioma:Inglês
Publicat: The Korean Association of Oral and Maxillofacial Surgeons 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949490/
https://ncbi.nlm.nih.gov/pubmed/24627836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5125/jkaoms.2014.40.1.3
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