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Intratumoral functional heterogeneity and chemotherapy

Intratumoral heterogeneity including genetic and nongenetic mechanisms refers to biological differences amongst malignant cells originated within the same tumor. Both, cell differentiation hierarchy and stochasticity in gene expression and signaling pathways may result in phenotypic differences of c...

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Bibliographic Details
Main Authors: Sipos, Ferenc, Constantinovits, Miklós, Műzes, Györgyi
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Co., Limited 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949253/
https://ncbi.nlm.nih.gov/pubmed/24627580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i10.2429
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