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Protein Function Annotation By Local Binding Site Surface Similarity

Hundreds of protein crystal structures exist for proteins whose function cannot be confidently determined from sequence similarity. Surflex-PSIM, a previously reported surface-based protein similarity algorithm, provides an alternative method for hypothesizing function for such proteins. The method...

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書目詳細資料
Main Authors: Spitzer, Russell, Cleves, Ann E., Varela, Rocco, Jain, Ajay N.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949165/
https://ncbi.nlm.nih.gov/pubmed/24166661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24450
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