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The immune system and the remodeling infarcted heart: cell biological insights and therapeutic opportunities
Extensive necrosis of ischemic cardiomyocytes in the infarcted myocardium activates the innate immune response triggering an intense inflammatory reaction. Release of danger signals from dying cells and damaged matrix activates the complement cascade and stimulates Toll-Like Receptor (TLR)/Interleuk...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949163/ https://ncbi.nlm.nih.gov/pubmed/24072174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000003 |
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