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Inhibition of APE1/Ref-1 redox activity rescues human retinal pigment epithelial cells from oxidative stress and reduces choroidal neovascularization

The effectiveness of current treatment for age related macular degeneration (AMD) by targeting one molecule is limited due to its multifactorial nature and heterogeneous pathologies. Treatment strategy to target multiple signaling pathways or pathological components in AMD pathogenesis is under inve...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Li, Y., Liu, X., Zhou, T., Kelley, M.R., Edwards, P., Gao, H., Qiao, X.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949093/
https://ncbi.nlm.nih.gov/pubmed/24624338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2014.01.023
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