GLP-1 receptor signaling is not required for reduced body weight after RYGB in rodents

Exaggerated GLP-1 and PYY secretion is thought to be a major mechanism in the reduced food intake and body weight after Roux-en-Y gastric bypass surgery. Here, we use complementary pharmacological and genetic loss-of-function approaches to test the role of increased signaling by these gut hormones i...

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Bibliographische Detailangaben
Hauptverfasser: Ye, Jianping, Hao, Zheng, Mumphrey, Michael B., Townsend, R. Leigh, Patterson, Laurel M., Stylopoulos, Nicholas, Münzberg, Heike, Morrison, Christopher D., Drucker, Daniel J., Berthoud, Hans-Rudolf
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2014
Schlagworte:
Neural Control
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949077/
https://ncbi.nlm.nih.gov/pubmed/24430883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00491.2013
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