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NFAT transcription factor regulation by urocortin II in cardiac myocytes and heart failure

Urocortin II (UcnII), a cardioactive peptide with beneficial effects in normal and failing hearts, is also arrhythmogenic and prohypertrophic. We demonstrated that cardiac effects are mediated by a phosphatidylinositol-3 kinase (PI3K)/Akt kinase (Akt)/endothelial nitric oxide synthase (eNOS)/nitric...

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Detalhes bibliográficos
Main Authors: Walther, Stefanie, Awad, Sawsan, Lonchyna, Vassyl A., Blatter, Lothar A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949047/
https://ncbi.nlm.nih.gov/pubmed/24441548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00353.2013
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