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Inhibitory signaling by CB(1) receptors in smooth muscle mediated by GRK5/β-arrestin activation of ERK1/2 and Src kinase
We examined whether CB(1) receptors in smooth muscle conform to the signaling pattern observed with other G(i)-coupled receptors that stimulate contraction via two Gβγ-dependent pathways (PLC-β3 and phosphatidylinositol 3-kinase/integrin-linked kinase). Here we show that the anticipated Gβγ-dependen...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949025/ https://ncbi.nlm.nih.gov/pubmed/24407588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00397.2013 |
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