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Early mitochondrial dysfunction in glycolytic muscle, but not oxidative muscle, of the fructose-fed insulin-resistant rat

Although evidence that type 2 diabetes mellitus (T2DM) is accompanied by mitochondrial dysfunction in skeletal muscle has been accumulating, a causal link between mitochondrial dysfunction and the pathogenesis of the disease remains unclear. Our study focuses on an early stage of the disease to dete...

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Main Authors: Warren, Blair E., Lou, Phing-How, Lucchinetti, Eliana, Zhang, Liyan, Clanachan, Alexander S., Affolter, Andreas, Hersberger, Martin, Zaugg, Michael, Lemieux, Hélène
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948982/
https://ncbi.nlm.nih.gov/pubmed/24425766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00511.2013
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