Pharmacological Inhibition of Cochlear Mitochondrial Respiratory Chain Induces Secondary Inflammation in the Lateral Wall: A Potential Therapeutic Target for Sensorineural Hearing Loss

Cochlear lateral wall has recently been reported as a common site of inflammation, yet precise molecular mechanisms of the inflammatory responses remain elucidated. The present study examined the inflammatory responses in the lateral wall following acute mitochondrial dysfunction induced by a mitoch...

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Detalhes bibliográficos
Main Authors: Fujioka, Masato, Okamoto, Yasuhide, Shinden, Seiichi, Okano, Hirotaka James, Okano, Hideyuki, Ogawa, Kaoru, Matsunaga, Tatsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948682/
https://ncbi.nlm.nih.gov/pubmed/24614528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090089
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