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Influenza virus NS1 protein inhibits pre-mRNA splicing and blocks mRNA nucleocytoplasmic transport.

The influenza virus RNA segment 8 encodes two proteins, NS1 and NS2, by differential splicing. The collinear transcript acts as mRNA for NS1 protein, while the spliced mRNA encodes NS2 protein. The splicing of NS1 mRNA was studied in cells transfected with a recombinant plasmid that has the cDNA of...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:EMBO J
Principais autores: Fortes, P, Beloso, A, Ortín, J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1994
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394862/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8313914/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06310.x
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