Linking Microcircuit Dysfunction to Cognitive Impairment: Effects of Disinhibition Associated with Schizophrenia in a Cortical Working Memory Model

Excitation–inhibition balance (E/I balance) is a fundamental property of cortical microcircuitry. Disruption of E/I balance in prefrontal cortex is hypothesized to underlie cognitive deficits observed in neuropsychiatric illnesses such as schizophrenia. To elucidate the link between these phenomena,...

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Bibliografiska uppgifter
Huvudupphovsmän: Murray, John D., Anticevic, Alan, Gancsos, Mark, Ichinose, Megan, Corlett, Philip R., Krystal, John H., Wang, Xiao-Jing
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
Feature Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948492/
https://ncbi.nlm.nih.gov/pubmed/23203979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhs370
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