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Resistance of LPS-activated bone marrow derived macrophages to apoptosis mediated by dexamethasone
Glucocorticoids (GC) display pleiotropic effects on the immune system. Macrophages are a major target for GC action. Here we show that dexamethasone (DEX), a synthetic GC, decreased viability of naïve bone marrow-derived macrophages (BMDM), involving an apoptotic mechanism. Administration of DEX tog...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3948355/ https://ncbi.nlm.nih.gov/pubmed/24608810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04323 |
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