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Analysis of the tumor-initiating and metastatic capacity of PDX1-positive cells from the adult pancreas
Pancreatic cancer is one of the deadliest human malignancies. A striking feature of pancreatic cancer is that activating Kras mutations are found in ∼90% of cases. However, apart from a restricted population of cells expressing pancreatic and duodenal homeobox 1 (PDX1), most pancreatic cells are ref...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3948305/ https://ncbi.nlm.nih.gov/pubmed/24550494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319911111 |
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