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MHC-dependent inhibition of uterine NK cells impedes fetal growth and decidual vascular remodelling

NK cells express variable receptors that engage polymorphic MHC class I molecules and regulate their function. Maternal NK cells accumulate at the maternal-fetal interface and can interact with MHC class I molecules from both parents. The relative contribution of the two sets of parental MHC molecul...

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Detalhes bibliográficos
Main Authors: Kieckbusch, Jens, Gaynor, Louise M., Moffett, Ashley, Colucci, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948146/
https://ncbi.nlm.nih.gov/pubmed/24577131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4359
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