Propofol compared with isoflurane inhibits mitochondrial metabolism in immature swine cerebral cortex

Anesthetics used in infants and children are implicated in the development of neurocognitive disorders. Although propofol induces neuroapoptosis in developing brain, the underlying mechanisms require elucidation and may have an energetic basis. We studied substrate utilization in immature swine anes...

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Detalhes bibliográficos
Main Authors: Kajimoto, Masaki, Atkinson, Douglas B, Ledee, Dolena R, Kayser, Ernst-Bernhard, Morgan, Phil G, Sedensky, Margaret M, Isern, Nancy G, Des Rosiers, Christine, Portman, Michael A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948133/
https://ncbi.nlm.nih.gov/pubmed/24398942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.229
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