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Activation and regulation of cellular inflammasomes: gaps in our knowledge for central nervous system injury

The inflammasome is an intracellular multiprotein complex involved in the activation of caspase-1 and the processing of the proinflammatory cytokines interleukin-1β (IL-1β) and IL-18. The inflammasome in the central nervous system (CNS) is involved in the generation of an innate immune inflammatory...

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Detalhes bibliográficos
Main Authors: de Rivero Vaccari, Juan Pablo, Dietrich, W Dalton, Keane, Robert W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948131/
https://ncbi.nlm.nih.gov/pubmed/24398940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.227
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