Methotrexate-Induced Neurotoxicity and Leukoencephalopathy in Childhood Acute Lymphoblastic Leukemia

PURPOSE: Methotrexate (MTX) can cause significant clinical neurotoxicity and asymptomatic leukoencephalopathy. We sought to identify clinical, pharmacokinetic, and genetic risk factors for these MTX-related toxicities during childhood acute lymphoblastic leukemia (ALL) therapy and provide data on sa...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Bhojwani, Deepa, Sabin, Noah D., Pei, Deqing, Yang, Jun J., Khan, Raja B., Panetta, John C., Krull, Kevin R., Inaba, Hiroto, Rubnitz, Jeffrey E., Metzger, Monika L., Howard, Scott C., Ribeiro, Raul C., Cheng, Cheng, Reddick, Wilburn E., Jeha, Sima, Sandlund, John T., Evans, William E., Pui, Ching-Hon, Relling, Mary V.
Format: Artigo
Langue:Inglês
Publié: American Society of Clinical Oncology 2014
Sujets:
ORIGINAL REPORTS
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948096/
https://ncbi.nlm.nih.gov/pubmed/24550419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2013.53.0808
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires