Physiological Relevance of LL-37 Induced Bladder Inflammation and Mast Cells

PURPOSE: We established the physiological relevance of LL-37 induced bladder inflammation. We hypothesized that 1) human urinary LL-37 is increased in pediatric patients with spina bifida, 2) LL-37 induced inflammation occurs in our mouse model via urothelial binding and is dose dependent and 3) LL-...

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Bibliografiske detaljer
Main Authors: Oottamasathien, Siam, Jia, Wanjian, Roundy, Lindsi McCoard, Zhang, Jianxing, Wang, Li, Ye, Xiangyang, Hill, A. Cameron, Savage, Justin, Lee, Wong Yong, Hannon, Ann Marie, Milner, Sylvia, Prestwich, Glenn D.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947931/
https://ncbi.nlm.nih.gov/pubmed/23313203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2013.01.002
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