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Metrics other than potency reveal systematic variation in responses to cancer drugs
Large-scale analysis of cellular response to anti-cancer drugs typically focuses on variation in potency (IC(50)) assuming that it is the most important difference between effective/ineffective drugs or sensitive/resistant cells. We took a multi-parametric approach involving analysis of the slope of...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947796/ https://ncbi.nlm.nih.gov/pubmed/24013279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1337 |
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