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Intracellular pathogen detection by RIG-I-like receptors

The RIG-I-like receptors (RLR) RIG-I, MDA5 and LGP2 trigger innate immune responses against viral infections that serve to limit virus replication and to stimulate adaptive immunity. RLRs are cytosolic sensors for virus-derived RNA and thus responsible for intracellular immune surveillance against i...

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Bibliographic Details
Main Authors: Dixit, Evelyn, Kagan, Jonathan C.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947775/
https://ncbi.nlm.nih.gov/pubmed/23611287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-410524-9.00004-9
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