Vasodilation by GPER in mesenteric arteries involves both endothelial nitric oxide and smooth muscle cAMP signaling

Our previous work showed that chronic activation of the membrane-bound estrogen receptor GPR30/GPER significantly lowers blood pressure in ovariectomized hypertensive mRen2.Lewis female rats which may, in part, reflect direct vasodilatory actions. The current study assessed the hypothesis that cycli...

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Bibliographic Details
Main Authors: Lindsey, Sarah H., Liu, Liu, Chappell, Mark C.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947732/
https://ncbi.nlm.nih.gov/pubmed/24246735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2013.10.017
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