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mRNA–mRNA duplexes that auto-elicit Staufen1-mediated mRNA decay
We report a new mechanism by which human mRNAs crosstalk: an Alu element in the 3'-untranslated region (3' UTR) of one mRNA can base-pair with a partially complementary Alu element in the 3' UTR of a different mRNA thereby creating a Staufen1 (STAU1)-binding site (SBS). STAU1 binding...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947523/ https://ncbi.nlm.nih.gov/pubmed/24056942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2664 |
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