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Integrin β1 Mediated Matrix Assembly and Signaling is Critical for the Normal Development and Function of the Kidney Glomerulus

The human kidneys filter 180 liters of blood every day via about 2.5 million glomeruli. The three layers of the glomerular filtration apparatus consists of fenestrated endothelium, specialized extracellular matrix known as the glomerular basement membrane (GBM) and the podocyte foot processes with t...

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Main Authors: Kanasaki, Keizo, Kanda, Yoshiko, Palmsten, Kristin, Tanjore, Harikrishna, Lee, Soo Bong, Lebleu, Valerie S., Gattone, Vincent H., Kalluri, Raghu
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947521/
https://ncbi.nlm.nih.gov/pubmed/18082680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.10.047
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