The influence of collagen–glycosaminoglycan scaffold relative density and microstructural anisotropy on tenocyte bioactivity and transcriptomic stability

Biomaterials for orthopedic tissue engineering must balance mechanical and bioactivity concerns. This work describes the fabrication of a homologous series of anisotropic collagen–GAG (CG) scaffolds with aligned tracks of ellipsoidal pores but increasing relative densities (ρ*/ρ(s)), and we report t...

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Hauptverfasser: Caliari, Steven R., Weisgerber, Daniel W., Ramirez, Manuel A., Kelkhoff, Douglas O., Harley, Brendan A.C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947516/
https://ncbi.nlm.nih.gov/pubmed/22658152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmbbm.2011.12.004
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