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microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma

Great interest persists in useful prognostic and therapeutic targets in glioblastoma (GBM). In this study, we report the definition of miR-148a as a novel prognostic oncomiR in GBM. miR-148a expression was elevated in human GBM specimens, cell lines and stem cells (GSCs) compared to normal human bra...

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Detalles Bibliográficos
Main Authors: Kim, Jungeun, Zhang, Ying, Skalski, Michael, Hayes, Josie, Kefas, Benjamin, Schiff, David, Purow, Benjamin, Parsons, Sarah, Lawler, Sean, Abounader, Roger
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947487/
https://ncbi.nlm.nih.gov/pubmed/24425048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1449
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