Physical and functional interactions between p53 and cell cycle co-operating transcription factors, E2F1 and DP1.

One way in which wild-type p53 is able to regulate cell cycle progression is thought to be via the induction of its downstream target gene Waf1/CIP1, thus indirectly regulating the transcriptional activity of E2F. The E2F transcription factors are known to be key effectors of the cell cycle. We repo...

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Autors principals: O'Connor, D J, Lam, E W, Griffin, S, Zhong, S, Leighton, L C, Burbidge, S A, Lu, X
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC394743/
https://ncbi.nlm.nih.gov/pubmed/8557038
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