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Reduction of excessive alcohol drinking by a novel GABA(B) receptor positive allosteric modulator ADX71441 in mice

RATIONALE: A promising pharmacotherapy for alcohol use disorders has been positive allosteric modulators (PAMs) of the γ-aminobutyric acid receptor B (GABA(B) R) since GABA(B) R PAMs reduce ethanol drinking and self-administration in rodents. OBJECTIVE: The current studies investigated a novel, sele...

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Библиографические подробности
Главные авторы: Hwa, Lara S., Kalinichev, Mikhail, Haddouk, Hasnaà, Poli, Sonia, Miczek, Klaus A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947346/
https://ncbi.nlm.nih.gov/pubmed/23975038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-013-3245-z
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