Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase.

Double-stranded RNA-dependent protein kinase (PKR) has been implicated in interferon (IFN) induction, antiviral response and tumor suppression. We have generated mice devoid of functional PKR (Pkr%). Although the mice are physically normal and the induction of type I IFN genes by poly(I).poly(C) (pI...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yang, Y L, Reis, L F, Pavlovic, J, Aguzzi, A, Schäfer, R, Kumar, A, Williams, B R, Aguet, M, Weissmann, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC394734/
https://ncbi.nlm.nih.gov/pubmed/8557029
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados