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Epigenetic silencing of CHD5, a novel tumor suppressor gene, occurs in early colorectal cancer stages
BACKGROUND: The chromodomain helicase DNA binding protein 5 (CHD5) is a family member of chromatin remodeling factors. The epigenetic silencing mechanisms of CHD5 in colorectal cancer (CRC) has not been well studied. METHODS: Here we analyzed the CHD5 methylation and mRNA expression in vitro and in...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947327/ https://ncbi.nlm.nih.gov/pubmed/24243398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28316 |
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