Neuron-specific (pro)renin receptor knockout prevents the development of salt-sensitive hypertension

The (pro)renin receptor, which binds both renin and prorenin, is a newly discovered component of the renin angiotensin system that is highly expressed in the central nervous system. The significance of brain PRRs in mediating local angiotensin II formation and regulating blood pressure remains uncle...

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Autors principals: Li, Wencheng, Peng, Hua, Mehaffey, Eamonn P., Kimball, Christie D., Grobe, Justin L., van Gool, Jeanette M.G., Sullivan, Michelle N., Earley, Scott, Danser, A.H. Jan, Ichihara, Atsuhiro, Feng, Yumei
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947277/
https://ncbi.nlm.nih.gov/pubmed/24246383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.113.02041
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