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Neuron-specific (pro)renin receptor knockout prevents the development of salt-sensitive hypertension

The (pro)renin receptor, which binds both renin and prorenin, is a newly discovered component of the renin angiotensin system that is highly expressed in the central nervous system. The significance of brain PRRs in mediating local angiotensin II formation and regulating blood pressure remains uncle...

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Bibliographic Details
Main Authors: Li, Wencheng, Peng, Hua, Mehaffey, Eamonn P., Kimball, Christie D., Grobe, Justin L., van Gool, Jeanette M.G., Sullivan, Michelle N., Earley, Scott, Danser, A.H. Jan, Ichihara, Atsuhiro, Feng, Yumei
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947277/
https://ncbi.nlm.nih.gov/pubmed/24246383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.113.02041
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