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A comparative study of Pointed and Yan expression reveals new complexity to the transcriptional networks downstream of receptor tyrosine kinase signaling

The biochemical regulatory network downstream of receptor tyrosine kinase (RTK) signaling is controlled by two opposing ETS family members: the transcriptional activator Pointed (Pnt) and the transcriptional repressor Yan. A bistable switch model has been invoked to explain how pathway activation ca...

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Detalhes bibliográficos
Main Authors: Lachance, Jean-François Boisclair, Peláez, Nicolás, Cassidy, Justin J., Webber, Jemma L., Rebay, Ilaria, Carthew, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947276/
https://ncbi.nlm.nih.gov/pubmed/24240101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.11.002
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