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Trigger factor is involved in GroEL-dependent protein degradation in Escherichia coli and promotes binding of GroEL to unfolded proteins.

In Escherichia coli, the molecular chaperones of hsp60/hsp10 (GroEL/GroES) families are required not only for protein folding but also for the rapid degradation of certain abnormal proteins. The rate-limiting step in the degradation of the fusion protein CRAG by protease ClpP appears to be the forma...

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Publicat a:EMBO J
Autors principals: Kandror, O, Sherman, M, Rhode, M, Goldberg, A L
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394722/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8846794/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00290.x
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