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Fragment-based error estimation in biomolecular modeling

Computer simulations are becoming an increasingly more important component of drug discovery. Computational models are now often able to reproduce and sometimes even predict outcomes of experiments. Still, potential energy models such as force fields contain significant amounts of bias and imprecisi...

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Detalhes bibliográficos
Main Authors: Faver, John C., Merz, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947206/
https://ncbi.nlm.nih.gov/pubmed/23993915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2013.08.016
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