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A unified GMDR method for detecting gene-gene interactions in family and unrelated samples with application to nicotine dependence

Gene-gene and gene-environment interactions govern a substantial portion of the variation in complex traits and diseases. In convention, a set of either unrelated or family samples are used in detection of such interactions; even when both kinds of data are available, the unrelated and the family sa...

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Main Authors: Chen, Guo-Bo, Liu, Nianjun, Klimentidis, Yann C., Zhu, Xiaofeng, Zhi, Degui, Wang, Xujing, Lou, Xiang-Yang
格式: Artigo
語言:Inglês
出版: 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947150/
https://ncbi.nlm.nih.gov/pubmed/24057800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-013-1361-9
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