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Axotomized neonatal motoneurons overexpressing the bcl2 proto-oncogene retain functional electrophysiological properties.

Bcl2 overexpression prevents axotomy-induced neuronal death of neonatal facial motoneurons, as defined by morphological criteria. However, the functional properties of these surviving lesioned transgenic neurons are unknown. Using transgenic mice overexpressing the protein Bcl2, we have investigated...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Alberi, S, Raggenbass, M, de Bilbao, F, Dubois-Dauphin, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1996
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39471/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8633001/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.9.3978
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