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Intracellular trafficking of furin is modulated by the phosphorylation state of a casein kinase II site in its cytoplasmic tail.

Human furin catalyzes the proteolytic maturation of many proproteins in the exocytic and endocytic secretory pathways by cleavage at the C-terminal side of the consensus sequence-ArgXaaLys/ArgArg decreases -. Both the trans-Golgi network (TGN) concentration and intracellular routing of furin require...

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Detalhes bibliográficos
Main Authors: Jones, B G, Thomas, L, Molloy, S S, Thulin, C D, Fry, M D, Walsh, K A, Thomas, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC394705/
https://ncbi.nlm.nih.gov/pubmed/8846780
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