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A large QTL for fear and anxiety mapped using an F(2) cross can be dissected into multiple smaller QTLs

Using chromosome substitution strains (CSS), we previously identified a large quantitative trait locus (QTL) for conditioned fear (CF) on mouse chromosome 10. Here, we used an F(2) cross between CSS-10 and C57BL/6J (B6) to localize that QTL to distal chromosome 10. That QTL accounted for all of the...

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Autori principali: Parker, Clarissa C., Sokoloff, Greta, Leung, Emily, Kirkpatrick, Stacey L., Palmer, Abraham A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947048/
https://ncbi.nlm.nih.gov/pubmed/23876074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12064
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