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Synthetic Antigens Reveal Dynamics of BCR Endocytosis During Inhibitory Signaling

B cells detect foreign antigens through their B cell antigen receptor (BCR). The BCR, when engaged by antigen, initiates a signaling cascade. Concurrent with signaling is endocytosis of the BCR complex, which acts to downregulate signaling and facilitate uptake of antigen for processing and display...

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Bibliografiset tiedot
Päätekijät: Courtney, Adam H., Bennett, Nitasha R., Zwick, Daniel B., Hudon, Jonathan, Kiessling, Laura L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947029/
https://ncbi.nlm.nih.gov/pubmed/24131142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400532y
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