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Lipidated cyclic γ-AApeptides display both antimicrobial and anti-inflammatory activity

Antimicrobial peptides (AMPs) are host-defense agents capable of both bacterial membrane disruption and immunomodulation. However, the development of natural AMPs as potential therapeutics is hampered by their moderate activity and susceptibility to protease degradation. Herein we report lipidated c...

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Detalhes bibliográficos
Main Authors: Li, Yaqiong, Smith, Christina, Wu, Haifan, Padhee, Shruti, Manoj, Namitha, Cardiello, Joseph, Qiao, Qiao, Cao, Chuanhai, Yin, Hang, Cai, Jianfeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947011/
https://ncbi.nlm.nih.gov/pubmed/24144063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb4006613
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