RANKL Inhibition With Denosumab Does Not Influence 3-year Progression of Aortic Calcification or Incidence of Adverse Cardiovascular Events in Postmenopausal Women With Osteoporosis and High Cardiovascular Risk

Atherosclerosis and osteoporosis are chronic diseases that progress with age, and studies suggest aortic calcification, an indicator of atherosclerosis, is inversely associated with BMD. The OPG/RANK/RANKL system has been proposed as a shared regulatory system for bone and vasculature. Denosumab (DM...

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Autores principales: Samelson, Elizabeth J., Miller, Paul D., Christiansen, Claus, Daizadeh, Nadia S., Grazette, Luanda, Anthony, Mary S., Egbuna, Ogo, Wang, Andrea, Siddhanti, Suresh R, Cheung, AM, Franchimont, N, Kiel, Douglas P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946983/
https://ncbi.nlm.nih.gov/pubmed/23873632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2043
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