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Connective Tissue Growth Factor (CTGF/CCN2) Negatively Regulates BMP-2 Induced Osteoblast Differentiation and Signaling

Connective tissue growth factor (CTGF/CCN2) and bone morphogenetic protein (BMP)-2 are both produced and secreted by osteoblasts. Both proteins have been shown to have independent effects in regulating osteoblast proliferation, maturation and mineralization. However, how these two proteins interact...

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Autors principals: Mundy, Christina, Gannon, Maureen, Popoff, Steven N.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946942/
https://ncbi.nlm.nih.gov/pubmed/24127409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24491
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