Dasatinib (BMS-35482) interacts synergistically with docetaxel, gemcitabine, topotecan and doxorubicin in ovarian cancer cells with high SRC pathway activation and protein expression

PURPOSE: To explore the activity of dasatinib in combination with docetaxel, gemcitabine, topotecan and doxorubicin in ovarian cancer cells. EXPERIMENTAL DESIGN: Cells with previously determined SRC pathway and protein expression (SRC pathway/SRC protein: IGROV1, both high; SKOV3, both low) were tre...

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Библиографические подробности
Главные авторы: Teoh, Deanna, Jia, Jingquan, Nixon, Andrew B., Grace, Lisa, Adams, David J., Murphy, Susan K., Secord, Angeles Alvarez
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946897/
https://ncbi.nlm.nih.gov/pubmed/24407585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/IGC.0000000000000056
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