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Discovery of sialyl Lewis A and Lewis X modified protein cancer biomarkers using high density antibody arrays

We report on a high-dimensional method to globally profile glycoproteins that are modified with sialyl Lewis A or Lewis X glycans. Specifically, glycoproteins in serum or plasma are fractionated on a high-density antibody microarray (i.e., each are localized to their specific antibody spot) and are...

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Main Authors: Rho, Jung-hyun, Mead, Judson R., Wright, W. Shea, Brenner, Dean E., James, W. Stave, Gildersleeve, Jeffrey C., Lampe, Paul D.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946870/
https://ncbi.nlm.nih.gov/pubmed/24185138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2013.10.030
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