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Functional clustering of immunoglobulin superfamily proteins with protein-protein interaction information calibrated Hidden Markov model sequence-profiles

Secreted and cell surface-localized members of the immunoglobulin superfamily (IgSF) play central roles in regulating adaptive and innate immune responses, and are prime targets for the development of protein-based therapeutics. An essential activity of the ectodomains of these proteins is the speci...

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Autors principals: Yap, Eng-Hui, Rosche, Tyler, Almo, Steve, Fiser, Andras
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946809/
https://ncbi.nlm.nih.gov/pubmed/24246499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.11.009
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