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High Frequency of Fusion Transcripts Involving TCF7L2 in Colorectal Cancer: Novel Fusion Partner and Splice Variants

VTI1A-TCF7L2 was reported as a recurrent fusion gene in colorectal cancer (CRC), found to be expressed in three out of 97 primary cancers, and one cell line, NCI-H508, where a genomic deletion joins the two genes [1]. To investigate this fusion further, we analyzed high-throughput DNA and RNA sequen...

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Библиографические подробности
Главные авторы: Nome, Torfinn, Hoff, Andreas M., Bakken, Anne Cathrine, Rognum, Torleiv O., Nesbakken, Arild, Skotheim, Rolf I.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946716/
https://ncbi.nlm.nih.gov/pubmed/24608966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091264
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