Human heart rate: Heritability of resting and stress values in twin pairs, and influence of genetic variation in the adrenergic pathway at a micro-RNA motif in the 3’-UTR of cytochrome b561 (CYB561)

OBJECTIVE: To understand the role of genetic variation in the catecholamine biosynthetic pathway for control of human heart rate (HR). BACKGROUND: Human HR is an integrated cardiovascular trait predictive of morbidity and survival. Since the autonomic pathway exerts rapid control over the heart, we...

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Hauptverfasser: Zhang, Kuixing, Deacon, Dekker C., Rao, Fangwen, Schork, Andrew J., Fung, Maple M., Waalen, Jill, Schork, Nicholas J., Nievergelt, Caroline M., Chi, Neil C., O'Connor, Daniel T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946708/
https://ncbi.nlm.nih.gov/pubmed/24140660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2013.09.025
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