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AAV-Mediated Overexpression of Neuroserpin in the Hippocampus Decreases PSD-95 Expression but Does Not Affect Hippocampal-Dependent Learning and Memory

Neuroserpin is a serine protease inhibitor, or serpin, that is expressed in the nervous system and inhibits the protease tissue plasminogen activator (tPA). Neuroserpin has been suggested to play a role in learning and memory but direct evidence for such a role is lacking. Here we have used an adeno...

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Detalhes bibliográficos
Main Authors: Tsang, Vicky W. K., Young, Deborah, During, Matthew J., Birch, Nigel P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946662/
https://ncbi.nlm.nih.gov/pubmed/24608243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091050
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