Polymorphisms in the Insulin-Like Growth Factor Axis Are Associated with Gastrointestinal Cancer

INTRODUCTION: Numerous factors influence the development of gastrointestinal (GI) cancer. The insulin-like growth factor (IGF) axis plays a role in embryonic and postnatal growth and tissue repair. Elevated levels of IGFs, low levels of IGF binding proteins (IGFBPs) and over-expression of IGF recept...

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Main Authors: Ong, Jennie, Salomon, Jody, te Morsche, Rene H. M., Roelofs, Hennie M. J., Witteman, Ben J. M., Dura, Polat, Lacko, Martin, Peters, Wilbert H. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946608/
https://ncbi.nlm.nih.gov/pubmed/24608110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090916
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